The enter key works fine in Finder, but in other software, say FTP (I happen to use Captian FTP, its the closest thing to CUTEftp on the pc (the mac version of cute sux btw.)) if you hit enter in the FTP software. it either opens the file or transfers it.
a Global Rename key would be nice, enter, f2 whatever, just a global key that works across the board would be nice.
the Home and End keys are killing me too. I found a site that explains how to change it, it works for the most part.. but 2-3 apps (firefox and safari to name 2) dont work. but at least while coding it works. I of course didnt bookmark it, but search for it in google and its there.