Will Filters Kill Spam? – Nope, but they’ll help a lot. Over the holidays I received over 400 spam emails. I had one false positive, that was from someone using a mail server that had been blacklisted. I had 3 spams in my inbox. That’s not bad. That’s Spam Assassin.
(Thanks Keith, and to set your mind at ease, Spam Assassin handles base64 encoded emails just fine. Catches them just as effectively!)